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Global Regenerative Trade

Global OrthoBiologic Expands Its Operation Under the Name Global REGENERATIVE Group (GRG)

Global OrthoBiologic has announced today that it will expand its operation under the name Global
REGENERATIVE Group (GRG) with headquarters to remain in Miami, Florida
(globalregenerative.group) and will consist of 4 divisions, which will operate independently –
Trade, Academy, Care and Finance.
Miami, FL, January 16, 2019 –(PR.com)– Global OrthoBiologic, based in Miami, Florida, invests,
identifies, develops and markets ground-breaking medical technologies related to Regenerative Medicine
in the global market. Global OrthoBiologic is a privately-held medical technologies company specializing
in therapies that significantly enhance the body’s natural healing ability. The company has developed
extensive experience in the most advanced medical device industries. In the past several years, the
emphasis has been focused exclusively on Regenerative Medicine and stem cell technologies, products,
and therapies.
The technologies for stem cells are cutting edge, safe, clean and do not use any additives, enzymes, or
require culturing or growing of cells. Global OrthoBiologic consults with medical technology companies
that are startups and/or companies looking to expand and grow their business. Global OrthoBiologic has
built a comprehensive network of experts in Europe, South America, Middle East, Asia, and Australia.
The company partners with recognized medical facilities worldwide for evidence-based clinical medicine.
Global OrthoBiologic has announced today that it will expand its operation under the name Global
REGENERATIVE Group (GRG) with headquarters to remain in Miami, Florida
(globalregenerative.group) and will consist of 4 divisions, which will operate independently – Trade,
Academy, Care and Finance. GRG will continue to offer its wide range of medical products in
Regenerative Medicine in various fields of medicine through its Global REGENERATIVE Trade and will
expand its operation with new technologies. Global REGENERATIVE Academy will concentrate on
Medical Science and Education. Global REGENERATIVE Care will focus exclusively on Medical
Tourism. Global REGENERATIVE Finance will identify medical advancements to improve patient
outcome and speed patient recovery.
Mihail Blagoev, Vice President commented, “We are excited to continue our growth and understanding in
the Regenerative Medicine Industry. Expanding our experience and dedication in medical science and
education through positioned events on different continents will give an opportunity to more and more
physicians and medical institutions to benefit from the Academy experts and to learn about the new
advancements in Regenerative Medicine. I believe that our continued expansion will benefit our trading
operation, and that will increase dramatically GRG revenue and value.”
Randy Beimel, President commented, “I would like to thank all of our partners that believed in us and our
capabilities. All of you are significant proof for our success today to become one of the leaders in the
Regenerative Medicine Industry. I would like to add that our Finance operation will be the key for our
future success; we have seen many great ideas that stayed for years in the physician’s brains or at their

ORs. We would like to identify these great medical ideas to first of all help the patients heal faster, and
benefit GRG revenue and value.”

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The uniqueness of the Vivostat® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous Fibrin Sealant or Platelet Rich Fibrin (PRF®) without using cryoprecipitation and without the need for a separate thrombin component.


  • The Processor Unit is a non-sterile, reusable, fully automated device that controls the biochemical process.
  • The Processor Unit is used to process the patient’s blood and prepare the Vivostat® Fibrin Sealant or Vivostat PRF® solution.
Vivostat Processor Product
  • The Processor Unit is operated by a single button and a display keeps the nurse informed of the remaining process time and status at all times. No specific installation is required and the large wheelbase makes moving it easy.
  • The Processor Unit can be located in any room or corridor in the operating department. It is most often placed centrally between the operating theatres. This way one Processor Unit can supply a number of operating theatres.
  • In approx.  25 min a concentrated fibrin sealant or PRF® solution is prepared from the patient’s whole blood.
  • The Applicator Unit is a non-sterile, reusable, fully automated device that controls the delivery of the Vivostat® Fibrin Sealant or Vivostat PRF®.
Vivostat Processor Product
  • The large display and integrated microprocessor automatically primes the Spraypen® and informs the surgeon of the remaining volume of fibrin sealant/PRF® throughout the entire process.
  • Different spray modes can be selected depending on the actual procedure or area to be covered. Like the Processor Unit it has a large wheelbase and can easily be moved if required.
  • The disposable set comprises of two parts: A Preparation Kit used to prepare the fibrin sealant or PRF® solution before surgery, and an Application Kit used to activate and apply the fibrin sealant/PRF® solution.


  • Preparation Kit
    The Preparation Kit contains the specially designed Preparation Unit – a sterile disposable device in which the patient’s blood is collected, the biochemical process carried out, and the fibrin sealant or PRF® solution harvested.


  • The Application Kit
    The Application Kit contains the Spraypen®1 and all other items required to prepare the system for the delivery of the fibrin sealant or PRF® solution. The Spraypen® is a sterile, disposable, hand held device which delivers the fibrin sealant or PRF® solution to the tissue. The revolutionary and patented design offers the surgeon unparalleled freedom in controlling the application unlike any other product on the market today.


1Besides the Spraypen®, the Vivostat® system offers different types of applicators, e.g. the Endoscopic Applicator. For a full list of application devices click here

1-2-3 Spray

Three easy steps to prepare Vivostat® Fibrin Sealant or Vivostat PRF®

1. Draw blood from the Patient

Fibrin Prep With Blood Inside

At the time of surgery or up to 24 hours before1, citrate (supplied with the kit) is added to the Preparation Unit. 120 ml of the patient’s own blood is then drawn into the same unit.

2. Process the patient’s blood

Vivostat Processor 800

The Preparation Unit is placed in the Processor Unit. At the touch of a button the process starts; after approx. 25 minutes, an autologous fibrin or PRF® solution is ready for use. No thrombin or bovine components are added to the blood at any time.

3. Load the Applicator Unit and spray

Vivostat Display Applicator

The Fibrin or PRF® solution is easily loaded into the Applicator Unit and applied to the surgical site using one of the unique application devices (e.g. the Spraypen). 1This depends on the type of kit being used. Always consult the “Instructions for Use” supplied with the kit to determine the correct preparation.

The following video illustrates how to prepare and apply autologous fibrin sealant.

Presentation DVD from Vivostat A/S on Vimeo.