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Global Regenerative Trade


Euroresearch is a company of DySyn Group, a group acting in different areas, from pharmaceutical to agro-veterinary fields, from real estate to flight services. Since its foundation in 1983 Euroresearch developed technologies for biological products in wound healing area.

The knowledge in wound healing, in last 25 years, grew fast because of the evolution in the treatment of delayed healing wounds. In more than 20 years experience Euroresearch developed and continues to develop high technology products to satisfy the most advanced needs in this therapeutic area.




about the product



Biopad and Biospray are biological dressings constituted by equine native type I collagen.


Euroresearch’s wound dressings are ideal for the control of minor bleedings and for the management of any kind of ulcer and skin lesion, such as pressure sores, venous ulcers, diabetic foot, traumatic and surgical lesions.


The choice of horse collagen, having an identical aminoacid composition and effectiveness compared to bovine collagen, represents a technological and safety improvement with respect to existing devices for same intended use.


The manufacturing process of the device, using a non-denaturant procedure in the absence of proteolytic enzymes and carried out at low temperature, and in subsequent drying and irradiation of the device so the collagen retains its native triple helix structure, microfibrillar frame, molecular weight and sequence of polypeptide chains.







What is BIOPAD?

BIOPAD® is an ivory-white soft sponge, made exclusively of lyophilized type I native heterologous collagen extracted from horse flexor tendon, gelatine free, that keeps its native structure, specific to the bodys skin tissue. BIOPAD® is supplied sterile in a single package, for one-use only, and can be available in different sizes from 1×1 cm to 10×15 cm. The standard size is 5×5 cm. BIOPAD® can be cut to wound size and easily adapted to wound size and shape.

How does it work?

BIOPAD® is an active dressing, playing an active role in all stages of wound healing process, stimulating granulation tissue growth and enhancing regeneration tissues. It ensures:

1. balance between absorption and humidity at wound surface
2. gaseous exchange
3. barrier to prevent bacterial infections
4. it is completely non-adherent

BIOPAD® use is completely painless for the patient and does not require removal or change of dressing.

Brand strategy

Quick restoration of intactness of damaged surface is critical in the healing process: BIOPAD® is the ideal means for ensuring a fast recovery of the wounded area. BIOPAD® is a superior and most innovative dressing for the control of minor bleeding and for the local management of moderately to heavy exuding wounds including:

· Pressure sores,
· Donor sites and other bleeding surfaces,
· Dehisced surgical incisions,
· Draining wounds,
· Lacerations,
· Venous stasis ulcers,
· Diabetic ulcers,
· Partial and full thickness wounds,
· Post-laser surgery,
· Podiatric,
· Surgical and traumatic wounds.

The advantages of BIOPAD®’s use can be summarized in:

· Reduction of healing time
· Best quality of scarring
· Excellent results, even in difficult to treat ulcers
· Easiness of use
· Painless application
· Reduced dressing frequency
· Outpatient treatment (in acute phase)
· Home-treatment (subsequently the acute phase)




BIOSPRAY® is an advanced medication, available in powder form with spray atomiser, made of native type I collagen extracted from horse flexor tendon, telopeptides and gelatine free, that keeps its native structure, specific to the body’s skin tissue. A peculiar proprietary extraction process minimizes all the factors of potential allergenicity of the collagen (telopeptides, denaturation, hydrolysis, etc.) and characterizes BIOSPRAY® for a particular degree of purity and as excellent haemostat and modulator of the tissue repair process. BIOSPRAY® is designed to create a favourable environment at the wound site, protecting the wounded area, controlling the micro-environment of the lesion
and stopping minor bleedings, thus representing an effective and safe means for the healing of wounds. BIOSPRAY® is supplied sterile in a single package
(aluminium can) of 75ml, and may be re-used until exhaustion of the product.

How does it work?

The mechanism of action of BIOSPRAY® is consequent to: invasion of its structure by leukocytes and macrophages of the blood and of the tissue; digestion from the proteases of the above mentioned cells, entailing the plastic reconstruction of the injured tissues. BIOSPRAY® stimulates the development
and proliferation of the granulation tissue and it actively promotes healing; its
haemostatic action is exerted through its effect on platelets aggregation. Although BIOSPRAY® is not absorbed (it acts and exerts its activity locally,

without involving the systemic structure of the body), it activates the cellular
fibroblastic mechanism, spurring the production of endogenous collagen
responsible of wound healing. Last but not least, BIOSPRAY® favours the
biologic control of the pH of the tissue. BIOSPRAY® is ideal in first-aid to control capillary haemorrhages, shortening
the clotting time of flowing blood. From the medical point of view, the collagen
in spray powder form is useful and easy to be handled as haemostat and healing agent being directly applied on the wounded area, forming – after the
spontaneous elimination of the gaseous component used as propellant – a uniform, compact and porous layer.

Brand strategy

BIOSPRAY® is intended for the control of minor bleedings and for the local management of minor wounds, including cicatrisation of all kind of skin lesions and accidental wounds.
BIOSPRAY® is indicated in the treatment of minor burns, skin irritations, superficial wounds and ulcers, nappy and incontinence rash, excoriations and grazes and as haemostat. It has also to be noted its anesthetizing and pain- killing effect due to the local cooling of the treated area, caused by one or repeated spouts of gaseous compound generated by the application of the
sprayed powder. BIOSPRAY® may be easily used by doctors, nurses, home care providers, unlicensed care providers and by patient himself, representing an excellent first- aid device.




BIOPAD SILVER® is an ivory-white soft sponge, made of lyophilized type I native heterologous collagen and colloidal silver. Collagen is extracted from horse flexor tendon, gelatine free, that keeps its native structure, specific to the bodys skin tissue.  Colloidal silver preserves the integrity of the device and maintains the wound environment free from exogenous bacteria thanks to the action exerted in situ for the duration of the dressing.

BIOPAD SILVER® is supplied sterile in a single package, for one-use only, and can be available in different sizes from 1×1 cm to 10×15 cm. The standard size is 5×5 cm. BIOPAD® can be cut to wound size and easily adapted to wound size and shape.

How does it work?

BIOPAD SILVER® is a Medical Device, an active dressing for use as haemostat and adjuvant in the treatment of pressure ulcers, venous ulcers and diabetic foot ulcers, chronic and traumatologic skin lesions and acute and traumatic wounds.

It ensures:

  1. balance between absorption and humidity at wound surface
  2. gaseous exchange
  3. barrier to prevent bacterial infections
  4. integrity of the device and wound environment free from exogenous bacteria and materials
  5. it is completely non-adherent.


Local haemostat to be used in general surgical procedures, such as vascular reconstructive surgery, vascular surgery, carotid surgery, abdominal and gynecological surgery, orthopedic and trauma surgery, dentistry and in first aid to control capillary bleeding. Indicated for treatment of skin lesions of different etiology such as chronic skin ulcers with delayed healing, venous and diabetic ulcers, pressure ulcers, to stimulate the physiological process of wound healing. The product is absorbed and dissolves over time. The lesion must be checked every 2-3 days (every 24 hours in case of particularly exuding lesions).

Despite the limited content of harmless silver, it is recommended as a precautionary measure to avoid the use of the product in patients known to be hypersensitive or allergic to metals and silver in particular. Even in the absence of adverse reports of the product as a result of radiation treatment of patients with dressings of silver, it is advisable to remove the plaque before patients undergo magnetic resonance imaging or other tests that involve the use of radiation. The product is not-toxic.


Vivostat Logo


The uniqueness of the Vivostat® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous Fibrin Sealant or Platelet Rich Fibrin (PRF®) without using cryoprecipitation and without the need for a separate thrombin component.


  • The Processor Unit is a non-sterile, reusable, fully automated device that controls the biochemical process.
  • The Processor Unit is used to process the patient’s blood and prepare the Vivostat® Fibrin Sealant or Vivostat PRF® solution.
Vivostat Processor Product
  • The Processor Unit is operated by a single button and a display keeps the nurse informed of the remaining process time and status at all times. No specific installation is required and the large wheelbase makes moving it easy.
  • The Processor Unit can be located in any room or corridor in the operating department. It is most often placed centrally between the operating theatres. This way one Processor Unit can supply a number of operating theatres.
  • In approx.  25 min a concentrated fibrin sealant or PRF® solution is prepared from the patient’s whole blood.
  • The Applicator Unit is a non-sterile, reusable, fully automated device that controls the delivery of the Vivostat® Fibrin Sealant or Vivostat PRF®.
Vivostat Processor Product
  • The large display and integrated microprocessor automatically primes the Spraypen® and informs the surgeon of the remaining volume of fibrin sealant/PRF® throughout the entire process.
  • Different spray modes can be selected depending on the actual procedure or area to be covered. Like the Processor Unit it has a large wheelbase and can easily be moved if required.
  • The disposable set comprises of two parts: A Preparation Kit used to prepare the fibrin sealant or PRF® solution before surgery, and an Application Kit used to activate and apply the fibrin sealant/PRF® solution.


  • Preparation Kit
    The Preparation Kit contains the specially designed Preparation Unit – a sterile disposable device in which the patient’s blood is collected, the biochemical process carried out, and the fibrin sealant or PRF® solution harvested.


  • The Application Kit
    The Application Kit contains the Spraypen®1 and all other items required to prepare the system for the delivery of the fibrin sealant or PRF® solution. The Spraypen® is a sterile, disposable, hand held device which delivers the fibrin sealant or PRF® solution to the tissue. The revolutionary and patented design offers the surgeon unparalleled freedom in controlling the application unlike any other product on the market today.


1Besides the Spraypen®, the Vivostat® system offers different types of applicators, e.g. the Endoscopic Applicator. For a full list of application devices click here

1-2-3 Spray

Three easy steps to prepare Vivostat® Fibrin Sealant or Vivostat PRF®

1. Draw blood from the Patient

Fibrin Prep With Blood Inside

At the time of surgery or up to 24 hours before1, citrate (supplied with the kit) is added to the Preparation Unit. 120 ml of the patient’s own blood is then drawn into the same unit.

2. Process the patient’s blood

Vivostat Processor 800

The Preparation Unit is placed in the Processor Unit. At the touch of a button the process starts; after approx. 25 minutes, an autologous fibrin or PRF® solution is ready for use. No thrombin or bovine components are added to the blood at any time.

3. Load the Applicator Unit and spray

Vivostat Display Applicator

The Fibrin or PRF® solution is easily loaded into the Applicator Unit and applied to the surgical site using one of the unique application devices (e.g. the Spraypen). 1This depends on the type of kit being used. Always consult the “Instructions for Use” supplied with the kit to determine the correct preparation.

The following video illustrates how to prepare and apply autologous fibrin sealant.

Presentation DVD from Vivostat A/S on Vimeo.