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Global Regenerative Trade

BEAUTY-STEM

Adipose tissue purification kit for aesthetic surgery​

BEAUTY-STEM is a closed-circuit single-use kit for adipose tissue purification without any centrifuge and with a minimal manipulation. The system provides a highly regenerative adipose tissue ideal for Cosmetic volumization surgery.

The entire processing phase of the liposuctioned tissue occurs inside the device thanks to continuous saline solution washing. This allows to reduce the cellular stress eliminating any traumatic action that may damage the extracellular matrix and its essential trophic and anti-inflammatory function.

The sophisticated filtering and washing system preserves the entire vascular stromal niche architecture and volume of the lipoaspirate and improves the cells’ capacity to respond to regenerative stimuli.


The final purified product is a viscous and dense fluid with a high regenerative potential that preservs the volume and adipose cluster size of the lipoaspirate and can be used for several aesthetic procedures.

why us

TIME EFFICIENT

Processes up to 400 ml of adipose tissue in approximatelly 10 minutes. No centrifugation waiting time and machinary clean up. All-in-one system that processes, purifies a high quality lipoaspirate within one device. Ready to use autologous lipofilling.

MINIMAL MANIPULATION

Adipose tissue purification and processing. Preservation of the cells biological properties and maximization of the regenerative potential. Continuous saline solution washing eliminating any traumatic action that may damage the extracellular matrix. Sampling and processing in a sterile closed-circuit environment, eliminating the risk of contamination

EASY

Simple and reproducible technique while mantaining the highest standards for fat grafting. Compared to centrifugation, BEAUTY-STEM minimizes staff training, OR preparation and clean-up. Allows to repeat the procedure with the same kit on the same patient Multiple waste bag connection for large volume liposuction.

CONVENIENT

No centrifugation required. Single surgical time and day hospital procedure. Only 1 operator required. No machinery loan and maintenance.

Fast growing company

Engaged in developing

Innovative solutions

MEDICAL PROFESSIONALS

BEAUTY-STEM is a closed-circuit single-use kit for liposuction and processing of adipose tissue without any centrifugation. The final purified product is a viscous fluid with a high regenerative potential that can be used for several aesthetic procedures.

BURNS

Improvement of the natural healing process of burned tissues.

ULCERS

Ulcers reconstruction chronic ulcers regeneration.

ONCOLOGY

Volume restoration after tumor removal radiotherapy dystrophic skin (breast).

BREAST

Composite augmentation (implant and fat), rippling correction after breast augmentation, total autologous volume

BUTT

Volume augmentation (Safe Subcutaneous Technique) and BBL (Brasilian Butt Lift)

BODY

Remodeling and volume restoration of breast and gluteus area for esthetic  or reconstructive reasons.

SCARS

Treatment of hypertrophic scars and scar-related conditions (i.e. acne).

FACE

Restoration of facial volumes and youthfulness.

SURGICAL TECHNIQUE​

Infiltrate the Klein solution in the selected harvest site.

  1. Harvest the adipose tissue from the previously infiltrated area.
  2. Connect a saline bag to the device’s “WASH IN” valve and open the clamp to fill the device.
  3. Insert the harvested adipose tissue in the device’s “LIPO IN” valve.
  4. Support the purification of the adipose tissue using the spatula provided with the kit, with a gentle movement on the filter and without exerting any pressure.
  5. Once the final product acquires a clear yellow color, stop the saline solution flow.
  6. Retrieve the purified adipose tissue from the dedicated “LIPO OUT” valve with a syringe and use as needed.

SURGICAL TECHNIQUE

Infiltrate the Klein solution in the selected harvest site.

  1. Harvest the adipose tissue from the previously infiltrated area.
  2. Connect a saline bag to the device’s “WASH IN” valve and open the clamp to fill the device.
  3. Insert the harvested adipose tissue in the device’s “LIPO IN” valve.
  4. Support the purification of the adipose tissue using the spatula provided with the kit, with a gentle movement on the filter and without exerting any pressure.
  5. Once the final product acquires a clear yellow color, stop the saline solution flow.
  6. Retrieve the purified adipose tissue from the dedicated “LIPO OUT” valve with a syringe and use as needed.

60 ml Klein solution syringe

60 ml Vaclok syringe for lipo-aspiration

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REGENERATIVE LIPOFILLING FOR AESTHETIC AND PLASTIC SURGERY

BEAUTY-STEM

BEAUTY-STEM is a closed-circuit single-use kit for liposuction
and processing of adipose tissue without any centrifugation.
The final purified product is a viscous fluid with a high
regenerative potential that can be used for several aesthetic
procedures.

 

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SUPPORTING EVIDENCE

GYNECOLOGY

 

Microfractured and Purified Adipose Tissue (LipogemsTM system) Injections for Treatment of Atrophic Vaginitis
Jennifer Fantasia, Halland Chen, and Janice A. Santos Cortes
J Urol Res 3(7): 1073.

Autologous adipose tissue graft in the vulva in severe vulvar lichen sclerosus atrophicus: clinical case
Davide De Vita, Carmen Sciorio, Serena Spartano
September 2016 – Vol. 28 – N. 5 – Supplement – Quarterly – ISSN 2385 – 0868

Menopause: new frontiers in the treatment of urogenital atrophy
G.A. Casarotti, P. Chiodera, C. Tremolada
European Review for Medical and Pharmacological Sciences 2018; 22: 567-574

 

 

BASIC SCIENCE

 

Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue

Sara Nava, Valeria Sordi, Luisa Pascucci, Carlo Tremolada, Emilio Ciusani, Offer Zeira, Moris Cadei, Gianni Soldati, Augusto Pessina,
Eugenio Parati, Mark Slevin and Giulio Alessandri
Hindawi
Stem Cells International
Volume 2019, Article ID 5901479, 13 pages
https://doi.org/10.1155/2019/5901479

A New Nonenzymatic Method and Device to Obtain a Fat Tissue Derivative Highly Enriched in Pericyte-Like Elements by Mild Mechanical Forces from Human Lipoaspirates
Francesca Bianchi, Margherita Maioli, Erika Leonardi,§ Elena Olivi, Gianandrea Pasquinelli, Sabrina Valente, Armando J. Mendez,
Camillo Ricordi, Mirco Raffaini, Carlo Tremolada and Carlo Ventura
Cell Transplantation, Vol. 22, pp. 2063–2077, 2013

Lipogems, a New Modality of Fat Tissue Handling to Enhance Tissue Repair in Chronic Hind Limb Ischemia
F. Bianchi, E. Olivi, M. Baldassarre, F.A. Giannone, M. Lagge-a, S. Valente, C. Cavallini, R. Tassinari, S. Canaider, G. Pasquinelli, C.
Tremolada, C. Ventura
CellR4 2014; 2 (6): e1289

Human Lipoaspirate as Autologous Injectable Active Scaffold for One-Step Repair of Cartilage Defects
Michela Bosetti, Alessia Borrone, Antonia Follenzi, Fanuel Messaggio, Carlo Tremolada and Mario Cannas
Cell Transplantation, Vol. 25, pp. 1043–1056, 2016

Characteristics and Properties of Mesenchymal Stem Cells Derived from Microfragmented Adipose Tissue
Stephana Carelli, Fanuel Messaggio, Alessandra Canazza, Danuta Maria Hebda, Filippo Caremoli, Elisa Latorre, Maria Grazia
Grimoldi, Mattia Colli, Gaetano Bulfamante, Carlo Tremolada, Anna Maria Di Giulio and Alfredo Gorio
Cell Transplantation, Vol. 24, pp. 1233–1252, 2015

 

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THE VIVOSTAT® SYSTEM

The uniqueness of the Vivostat® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous Fibrin Sealant or Platelet Rich Fibrin (PRF®) without using cryoprecipitation and without the need for a separate thrombin component.

THE FULLY AUTOMATED VIVOSTAT® SYSTEM CONSISTS OF THREE COMPONENTS: