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Global Regenerative Trade

BIOPAD AND BIOSPRAY

Euroresearch is a company of DySyn Group, a group acting in different areas, from pharmaceutical to agro-veterinary fields, from real estate to flight services. Since its foundation in 1983 Euroresearch developed technologies for biological products in wound healing area.

The knowledge in wound healing, in last 25 years, grew fast because of the evolution in the treatment of delayed healing wounds. In more than 20 years experience Euroresearch developed and continues to develop high technology products to satisfy the most advanced needs in this therapeutic area.

NATURAL GROWING

NATURAL HEALING

INFORMATION

about the product

WHAT ARE EUROSEARCH’S WOUND DRESSING

BIOPAD AND BIOPAD SPRAY

Biopad and Biospray are biological dressings constituted by equine native type I collagen.

ANY KIND OF ULCER AND SKIN LESION

Euroresearch’s wound dressings are ideal for the control of minor bleedings and for the management of any kind of ulcer and skin lesion, such as pressure sores, venous ulcers, diabetic foot, traumatic and surgical lesions.

SAFETY IMPROVEMENT

The choice of horse collagen, having an identical aminoacid composition and effectiveness compared to bovine collagen, represents a technological and safety improvement with respect to existing devices for same intended use.

NON-DENATURANT PROCEDURE

The manufacturing process of the device, using a non-denaturant procedure in the absence of proteolytic enzymes and carried out at low temperature, and in subsequent drying and irradiation of the device so the collagen retains its native triple helix structure, microfibrillar frame, molecular weight and sequence of polypeptide chains.

STRUCTURE OF THE COL4A1 PROTEIN

OUR PRODUCTS

BIOPAD®

BIOSPRAY®

BIOPAD SILVER®

BIOPAD®

What is BIOPAD?

BIOPAD® is an ivory-white soft sponge, made exclusively of lyophilized type I native heterologous collagen extracted from horse flexor tendon, gelatine free, that keeps its native structure, specific to the bodys skin tissue. BIOPAD® is supplied sterile in a single package, for one-use only, and can be available in different sizes from 1×1 cm to 10×15 cm. The standard size is 5×5 cm. BIOPAD® can be cut to wound size and easily adapted to wound size and shape.

How does it work?

BIOPAD® is an active dressing, playing an active role in all stages of wound healing process, stimulating granulation tissue growth and enhancing regeneration tissues. It ensures:

1. balance between absorption and humidity at wound surface
2. gaseous exchange
3. barrier to prevent bacterial infections
4. it is completely non-adherent

BIOPAD® use is completely painless for the patient and does not require removal or change of dressing.

Brand strategy

Quick restoration of intactness of damaged surface is critical in the healing process: BIOPAD® is the ideal means for ensuring a fast recovery of the wounded area. BIOPAD® is a superior and most innovative dressing for the control of minor bleeding and for the local management of moderately to heavy exuding wounds including:

· Pressure sores,
· Donor sites and other bleeding surfaces,
· Dehisced surgical incisions,
· Draining wounds,
· Lacerations,
· Venous stasis ulcers,
· Diabetic ulcers,
· Partial and full thickness wounds,
· Post-laser surgery,
· Podiatric,
· Surgical and traumatic wounds.

The advantages of BIOPAD®’s use can be summarized in:

· Reduction of healing time
· Best quality of scarring
· Excellent results, even in difficult to treat ulcers
· Easiness of use
· Painless application
· Reduced dressing frequency
· Outpatient treatment (in acute phase)
· Home-treatment (subsequently the acute phase)

 

BIOSPRAY®

What is BIOSPRAY?

BIOSPRAY® is an advanced medication, available in powder form with spray atomiser, made of native type I collagen extracted from horse flexor tendon, telopeptides and gelatine free, that keeps its native structure, specific to the body’s skin tissue. A peculiar proprietary extraction process minimizes all the factors of potential allergenicity of the collagen (telopeptides, denaturation, hydrolysis, etc.) and characterizes BIOSPRAY® for a particular degree of purity and as excellent haemostat and modulator of the tissue repair process. BIOSPRAY® is designed to create a favourable environment at the wound site, protecting the wounded area, controlling the micro-environment of the lesion
and stopping minor bleedings, thus representing an effective and safe means for the healing of wounds. BIOSPRAY® is supplied sterile in a single package
(aluminium can) of 75ml, and may be re-used until exhaustion of the product.

How does it work?

The mechanism of action of BIOSPRAY® is consequent to: invasion of its structure by leukocytes and macrophages of the blood and of the tissue; digestion from the proteases of the above mentioned cells, entailing the plastic reconstruction of the injured tissues. BIOSPRAY® stimulates the development
and proliferation of the granulation tissue and it actively promotes healing; its
haemostatic action is exerted through its effect on platelets aggregation. Although BIOSPRAY® is not absorbed (it acts and exerts its activity locally,

without involving the systemic structure of the body), it activates the cellular
fibroblastic mechanism, spurring the production of endogenous collagen
responsible of wound healing. Last but not least, BIOSPRAY® favours the
biologic control of the pH of the tissue. BIOSPRAY® is ideal in first-aid to control capillary haemorrhages, shortening
the clotting time of flowing blood. From the medical point of view, the collagen
in spray powder form is useful and easy to be handled as haemostat and healing agent being directly applied on the wounded area, forming – after the
spontaneous elimination of the gaseous component used as propellant – a uniform, compact and porous layer.

Brand strategy

BIOSPRAY® is intended for the control of minor bleedings and for the local management of minor wounds, including cicatrisation of all kind of skin lesions and accidental wounds.
BIOSPRAY® is indicated in the treatment of minor burns, skin irritations, superficial wounds and ulcers, nappy and incontinence rash, excoriations and grazes and as haemostat. It has also to be noted its anesthetizing and pain- killing effect due to the local cooling of the treated area, caused by one or repeated spouts of gaseous compound generated by the application of the
sprayed powder. BIOSPRAY® may be easily used by doctors, nurses, home care providers, unlicensed care providers and by patient himself, representing an excellent first- aid device.

 

BIOPAD SILVER®

What is BIOPAD SILVER®

BIOPAD SILVER® is an ivory-white soft sponge, made of lyophilized type I native heterologous collagen and colloidal silver. Collagen is extracted from horse flexor tendon, gelatine free, that keeps its native structure, specific to the bodys skin tissue.  Colloidal silver preserves the integrity of the device and maintains the wound environment free from exogenous bacteria thanks to the action exerted in situ for the duration of the dressing.

BIOPAD SILVER® is supplied sterile in a single package, for one-use only, and can be available in different sizes from 1×1 cm to 10×15 cm. The standard size is 5×5 cm. BIOPAD® can be cut to wound size and easily adapted to wound size and shape.

How does it work?

BIOPAD SILVER® is a Medical Device, an active dressing for use as haemostat and adjuvant in the treatment of pressure ulcers, venous ulcers and diabetic foot ulcers, chronic and traumatologic skin lesions and acute and traumatic wounds.

It ensures:

  1. balance between absorption and humidity at wound surface
  2. gaseous exchange
  3. barrier to prevent bacterial infections
  4. integrity of the device and wound environment free from exogenous bacteria and materials
  5. it is completely non-adherent.

USAGE

Local haemostat to be used in general surgical procedures, such as vascular reconstructive surgery, vascular surgery, carotid surgery, abdominal and gynecological surgery, orthopedic and trauma surgery, dentistry and in first aid to control capillary bleeding. Indicated for treatment of skin lesions of different etiology such as chronic skin ulcers with delayed healing, venous and diabetic ulcers, pressure ulcers, to stimulate the physiological process of wound healing. The product is absorbed and dissolves over time. The lesion must be checked every 2-3 days (every 24 hours in case of particularly exuding lesions).

Despite the limited content of harmless silver, it is recommended as a precautionary measure to avoid the use of the product in patients known to be hypersensitive or allergic to metals and silver in particular. Even in the absence of adverse reports of the product as a result of radiation treatment of patients with dressings of silver, it is advisable to remove the plaque before patients undergo magnetic resonance imaging or other tests that involve the use of radiation. The product is not-toxic.

 

Vivostat Logo

THE VIVOSTAT® SYSTEM

The uniqueness of the Vivostat® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous Fibrin Sealant or Platelet Rich Fibrin (PRF®) without using cryoprecipitation and without the need for a separate thrombin component.

THE FULLY AUTOMATED VIVOSTAT® SYSTEM CONSISTS OF THREE COMPONENTS: