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Orthopedics, Sports medicine, Traumatology
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about the product
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A new molecule called external inorganic gel liquid magnet has been developed using a combination of silica, calcium chloride, and tetrahydropiperine, which have a very high water holding capacity.
It is applied as a layer with a minimum thickness of 3mm to cover the entire edema area that occurs after tissue trauma. The area of application is covered with sterile bandage for twelve hours.
Cosmoperine, which is found in the gel, supports increasing the fluid permeability by expanding the porous structure of dermis and epidermis.
Having a high water holding capacity the external inorganic gel liquid magnet, which is not absorbed into the skin, binds the edema liquid under the skin to the molecular structure thanks to free cylanol groups and restrains it in to the gel complex.
Silanol groups (Si-OH) are created by treating Silica (SiO2) in an alkali environment and bonding extra hydrophilic characteristics. Thus, the water retention properties of the product are increased, while the human skin cannot absorb it.
It is known that hydrophobic molecules of lesser weight transit from the stratum corneum layer easily.
There is not certain findings related to transition to lower layer of epidermis and dermis. In addition to this, it is reported that the molecules heavier than 500 Da cannot transit from stratum corneum layer.
Based on the information, silica (which has a high water extraction feature) has no skin permeability. This is because its ionic structure is different than that of the skin.
Therefore, silica will not be absorbed to the intradermal space, but the water retention properties allows silica to remove the extrafluid from the derma.
Calcium chloride is one of the most potent moisture absorbing compounds found in nature. As the second most commonly occurring substance in seawater next to salt, calcium chloride is also non-toxic and environmentally friendly. Calcium chloride is the active compound in Absortech products.
AEROPERL 300 Pharma is a granulated form of colloidal silicon dioxide. The spherical granules have a diameter of approximately 30 mm, giving the product a much higher tapped density of about 280 g/L compared to the non- granulated products. AEROPERL 300 Pharma can be used as an absorbent for liquid active pharmaceutical ingredients and as a moisture scavenger, e.g., in moisture activated dry granulation processes (MADG) as well as a high density and low dust glidant.
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1Besides the Spraypen®, the Vivostat® system offers different types of applicators, e.g. the Endoscopic Applicator. For a full list of application devices click here